Pulmonology

Temple Lung Center | Enrolling Clinical Trials

The Temple Lung Center conducts one of the most comprehensive lung disease clinical trials programs in the country. Our advancements in basic, translational and clinical research are changing lung disease treatment. By pioneering effective therapies, we bring hope to patients with serious and debilitating lung diseases. 
 

Review Our Open Clinical Trials

 


Asthma

A Dose Finding Study With an Anti-TSLP Antibody (GSK5784283) in Adults Aged 18 to 75 Years of Age With Uncontrolled Asthma
NCT06748053

Depemokimab Asthma Imaging and Bronchoscopy Sub-Study
NCT06979323

A Study to Test if a Fixed-Dose Combination of Fluticasone Propionate/?Albuterol Sulfate is Effective in Preventing Asthma Exacerbations
NCT06052267

Pragmatic Open - Label Randomized Clinical Trial of FF/?UMEC/?VI vs Non-ellipta Usual Care ICS-LABA for Adult Participants With Uncontrolled Asthma
 
A Study to Evaluate Solriktug in Adult Participants With Asthma (RAINIER)
 

 


Bronchiectasis

A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis

 

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COPD

Video Telehealth Pulmonary Rehabilitation to Reduce Hospital Readmission in Chronic Obstructive Pulmonary Disease
NCT05119556
 
Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3 (BREATHE-3)

NCT06891755

 
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (EMBARK)

NCT06883305

 
Temple Health Chest Initiative (THCI 2.0) - Lung Cancer Screening Project With COPD Detection
 
Long-term, Open-label Study of SAR447537 (INBRX-101) in Adults With Alpha-1 Antitrypsin Deficiency Emphysema (ELEVAATE OLE)
NCT05897424
 
STRIVE Post-Market Registry Study
 
Device myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home
NCT05204888
 
Biological Effects of Quercetin in COPD Phase II
 
An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema (CONVERT_II)
 
A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease (THARROS)
 
A Study to Evaluate Solrikitug in Participants With COPD (ZION)
 

 


Interstitial Lung Disease (ILD)

PH-ILD A Study of Mosliciguat in PH-ILD (PHocus)
NCT06635850


PH-ILD DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
NCT06388421

A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease (BEconneCTD-ILD)
NCT06572384

A Study to Test Whether BI 1819479 Improves Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF)
NCT06335303

Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)
NCT05943535

SSc-ILD A Study of the Efficacy and Safety of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease (BLISSc-ILD)
NCT05878717
 

Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension (MOMENTOUS)
NCT06911632

 
Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF)
 

A Phase 2 Study of CAL101 in Patients With Idiopathic Pulmonary Fibrosis (AURORA)
NCT06736990

 
A Study Evaluating the Safety and Efficacy of AP01 in Participants With Progressive Pulmonary Fibrosis (PPF)

 


Inpatient

Trial of Therapeutic Hypothermia in Patients With ARDS (CHILL)

 


Lung Cancer

Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening (PROACT-LUNG)

 


Lung Transplant

A Study to Test How Effective Belumosudil Tablets Are for Treating Adult Participants With Chronic Lung Allograft Dysfunction (ROCKaspire)

 


Mesothelioma

National Mesothelioma Virtual Registry and Tissue Bank (U19)

 


Pulmonary Vascular Disease

PH-ILD A Study of Mosliciguat in PH-ILD (PHocus)
NCT06635850
 

PH-ILD DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
NCT06388421

Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System
NCT04798261
 
Novel alpha2-Antiplasmin Inactivation for Lysis of Intravascular Thrombi (NAIL-IT) Trial (NAIL-IT)
NCT05408546

PH-COPD MK-5475-013 INSIGNIA-PH-COPD: A Study of the Efficacy and Safety of MK-5475 (an Inhaled sGC Stimulator) in Adults With PH-COPD
NCT05612035

PH-COPD The RAPID - PE Study: RESCUE Advanced Protocol for the Treatment of Pulmonary Embolism
NCT06433011

 


Sarcoidosis

Efficacy and Safety Study of OATD-01 in Patients With Active Pulmonary Sarcoidosis (KITE)
 

 


Other

American Lung Association (ALA) Lung Health Cohort
NCT04543461

 

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For more information about clinical research trials at the Temple Lung Center,
email breathebetter@tuhs.temple.edu or call 215-707-1359.