John F. McDyer, MD

Education

BS, Chemistry, St. Joseph's University, Philadelphia, 1986

MD, Thomas Jefferson Medical College, 1990

 

Training

Residency, Internal Medicine, Barnes Hospital, Washington University, 1993

Fellowship, Allergy/Immunology, National Institute of Allergy and Infectious Diseases, 1998

Fellowship, Critical Care/Pulmonary Medicine, NIH Bethesda and Johns Hopkins University, 2002

 

Research Interest

CMV infection remains the most common infection in lung transplant recipients (LTRs) and a major cause of morbidity and mortality. Dr McDyer’s research investigates T-bet, the T cell transcriptional factor to determine if it is necessary for protective CMV-specific immunity during acute and chronic CMV infection. To test this he uses both the murine CMV (MCMV) pulmonary infection model and the LTR cohort to study the role of T-bet in pulmonary and systemic CMV host defense and the development of protective T cell memory.